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Adaptive immunity depends upon the activity of what type of cells?


A) natural killer cells and B cells
B) natural killer cells and T cells
C) neutrophils and B cells
D) neutrophils and T cells
E) B cells and T cells

F) B) and E)
G) A) and E)

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Tissue rejection following organ transplantation is due to all of the following except


A) MHC incompatibility between donor and recipient.
B) transplantation of tissues from one part of the body to another in the same person.
C) the destruction of transplanted tissue by the immune system.
D) B cells and plasma cells that do not recognize the transplanted tissue as "self."
E) T cells that do not recognize the transplanted tissue as "self."

F) B) and D)
G) A) and C)

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Which of the following is NOT an example of innate immunity?


A) natural killer cells
B) complement
C) inflammation
D) histamine
E) plasma cells

F) A) and E)
G) A) and B)

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Inflammation or the inflammatory response is a harmful process that should be avoided.

A) True
B) False

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Which of the following is specifically responsible for antibody-mediated immunity?


A) T cell
B) B cell
C) platelets
D) RBC
E) complement

F) A) and E)
G) C) and D)

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The spleen has a relatively thin outer capsule and can actually burst due to a blow to the abdomen.A person whose spleen has burst


A) cannot survive.
B) cannot synthesize red blood cells.
C) cannot synthesize white blood cells.
D) may need antibiotic therapy.
E) may need blood transfusions to prevent anemia.

F) B) and C)
G) C) and D)

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In the late 1800s,a Frenchman observed that individuals who recovered from a disease were not susceptible to that same disease again.Therefore,he proposed that the agent that caused syphilis should be given to all young,healthy people as a vaccine to prevent them from getting a serious case of the disease.Although the mode of action of vaccines was not yet known,Pasteur argued vehemently against this proposal.Today,we do not follow this procedure for syphilis.Why?


A) Vaccines only work against a few pathogens.
B) Vaccines do not work for pathogens that are vulnerable to antibiotics.
C) Syphilis is an autoimmune disease.
D) It might work,but Pasteur was a famous authority and his ideas prevail today.
E) Vaccines are made from weakened disease agents and using the syphilis organisms would spread a full-blown serious disease agent.

F) None of the above
G) A) and B)

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Which of the following is NOT considered to be an innate defense mechanism against infection?


A) stomach acids
B) skin
C) mucus in respiratory tract
D) normal bacteria in intestine
E) antibodies in mother's milk

F) A) and B)
G) D) and E)

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Which of the following would not lead to an immunodeficiency?


A) inherited lack of B cells
B) blood transfusion
C) surgical removal of the thymus
D) SCID
E) AIDS

F) A) and E)
G) A) and B)

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Which of the following are NOT considered lymphoid organs?


A) bone marrow
B) thymus
C) spleen
D) lymph nodes
E) kidneys

F) A) and E)
G) C) and E)

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During organ transplant,which feature is the most important to recognize?


A) the difference between the MHC proteins of the donor and the recipient
B) the difference between the blood types of the donor and the recipient
C) the similarities between the blood types of the donor and the recipient
D) the type of organ being transplanted
E) the age of the recipient of the transplanted organ

F) A) and B)
G) A) and E)

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Which type of cell will produce antibodies that are released into the bloodstream?


A) B cell
B) T cell
C) plasma cell
D) memory cell
E) mast cell

F) A) and E)
G) B) and E)

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The clonal selection theory states that


A) all B cells are exact clones of one another.
B) all T cells are exact clones of one another.
C) when a B or T cell is activated by binding to/recognizing an antigen,then that cell will be cloned into cells that recognize the same antigen.
D) when a B or T cell is stimulated by encountering the correct antibody,it divides to form a clone of cells that will respond to the same antibody.
E) T cells are stimulated by B cells to divide and form plasma cells,which secrete antibodies.

F) B) and E)
G) C) and D)

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Which is NOT part of a description of an antibody molecule?


A) contains a constant and a variable region on each chain
B) forms an X-shaped protein molecule
C) contains an antigen-binding site on each arm
D) contains two light chains and two heavy chains
E) contains hypervariable regions where antigens bind

F) B) and D)
G) B) and C)

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Babies generally appear to be immune to diseases for approximately the first six months of life.After this,they develop more diseases.What could be responsible for this immunity?


A) active immunity due to the mother
B) passive immunity from the mother
C) babies not being exposed to diseases until around six months
D) babies born with excellent active immunity that wanes the older the child gets
E) active immunity due to being exposed to numerous antigens during the birthing process

F) A) and E)
G) A) and D)

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An antihistamine counters the effects of a histamine.Which of the following is NOT an effect of a histamine?


A) Increased blood flow brings more white blood cells to the site of injury or invasion.
B) Capillary dilation increases blood flow and causes surface redness.
C) Increased blood flow and permeability increase the fluids in the tissues,causing them to swell.
D) Increased blood flow brings more warmth to the area,causing a local "fever" that helps white blood cells and suppresses microbes.
E) Decreased blood flow inhibits a pathogen from spreading throughout the body.

F) A) and D)
G) B) and D)

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The complement system contains


A) either half of an antigen-antibody complex.
B) certain plasma proteins.
C) a serious infection.
D) an autoimmune reaction.
E) cells that secrete antibodies.

F) A) and B)
G) A) and C)

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Which lymphatic duct will drain the abdomen?


A) lymph capillaries
B) right lymphatic duct
C) left lymphatic duct
D) thoracic duct
E) inguinal duct

F) C) and D)
G) A) and D)

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How is a lymph capillary like a blood capillary?


A) Both contain blood.
B) Both contain valves.
C) Both have thin walls.
D) Both are connected to the vena cava.
E) Both systems run parallel through all body tissues.

F) All of the above
G) B) and E)

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In the later 1800s,the brilliant French chemist Louis Pasteur worked with chicken cholera,passing the disease agent from sick to healthy chickens.He suspended his research and went on vacation for several weeks.When he returned,the old cholera culture he gave to healthy chickens failed to kill them.He assumed his culture was bad and injected these same chickens with a fresh culture of chicken cholera.These chickens remained healthy while new chickens injected with the fresh culture of chicken cholera rapidly became sick and died.From our current knowledge of immunity,how would these observations be explained?


A) Pasteur had accidentally discovered a strain of chickens that had natural immunity.
B) His first disease culture had weakened over time and stimulated the development of active immunity.
C) His first disease culture had weakened over time and the chickens developed a form of passive immunity.
D) The chickens apparently had better B cells for development of more effective antibodies.
E) The first set of chickens served as a control group to the second set that showed the development of antibodies.

F) A) and B)
G) D) and E)

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