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Which of the following is a versatile carrier of several different one-carbon units?


A) pyridoxal phosphate
B) biotin
C) tetrahydrofolate
D) coenzyme A
E) None of the answers is correct.

F) A) and B)
G) A) and E)

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C

Chorismate is a precursor to the amino acids


A) tryptophan, tyrosine, and phenylalanine.
B) serine, glycine and cysteine.
C) isoleucine, leucine and valine.
D) methionine, threonine, and lysine.
E) None of the answers is correct.

F) A) and E)
G) D) and E)

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What molecule is an activated form of ribose phosphate and a precursor for histidine?


A) ribose triphosphate
B) PRPP (5-phosphoribosyl-1-pyrophosphate)
C) ATP
D) cyclic AMP
E) None of the answers is correct.

F) C) and D)
G) A) and B)

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What unusual (and not recommended)experiments were carried out by Shemin and colleagues?

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Acting as a human guinea pig,S...

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Essential amino acids (for humans) differ from nonessential amino acids in that


A) nonessential amino acids are synthesized in simple reaction pathways compared to complex pathways for most essential amino acids.
B) essential amino acids are generally synthesized directly from citric acid cycle intermediates, but not nonessential amino acids.
C) microorganisms and animals cannot synthesize essential amino acids but plants can.
D) animals cannot synthesize essential amino acids because they have lost the ability to carry out transamination reactions.
E) All of the answers are correct.

F) C) and D)
G) D) and E)

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A

This amino acid,in high levels,is correlated with the damage of cells lining the blood vessels.


A) serine
B) cysteine
C) S-adenosylmethionine
D) citrulline
E) homocysteine

F) B) and E)
G) All of the above

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The carbon skeletons used to synthesize amino acids are intermediates found in


A) glycolysis.
B) glycogen metabolism.
C) citric acid cycle.
D) All the answers are correct.
E) glycolysis and citric acid cycle

F) C) and D)
G) A) and B)

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E

How does the herbicide glyphosate work?

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Glyphosate (Roundup is one brand)acts by...

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What is the activated methyl cycle?

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The methyl group on the side-chain of me...

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How may have feedback inhibition processes evolved?


A) duplication of genes encoding catalytic domains
B) evolution of homologous subunits in the enzyme catalyzing the committed step
C) linking specific regulatory domains to catalytic domains
D) linking of multiple regulatory domains to one another
E) All of the answers are correct.

F) A) and B)
G) A) and C)

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What do S-adenosylmethionine and fruit ripening have in common?

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S-Adenosylmethionine is a prec...

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Which of the following is the original nitrogen source for the nitrogen found in amino acids?


A) atmospheric nitrogen (N2)
B) tetrahydrofolate
C) glutamine
D) ammonia (NH3)
E) urea

F) B) and E)
G) A) and D)

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Describe the structure and function of the FeMo cofactor.

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This unusual redox center is the site of...

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What process converts N2 to NH3?


A) urea cycle
B) glutamine hydrolysis
C) denitrification
D) nitrogen fixation
E) None of the answers is correct.

F) A) and E)
G) B) and D)

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Describe the process and proteins involved in nitrogen fixation.

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Electrons are provided by ferredoxin,tra...

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What amino acid is added to indole in the biosynthesis of tryptophan?


A) glutamine
B) serine
C) tyrosine
D) alanine
E) None of the answers is correct.

F) B) and E)
G) A) and C)

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An example of a reaction controlled by enzyme multiplicity is


A) phosphorylation of asparagine by aspartokinases.
B) phosphorylation of aspartate by aspartokinases.
C) phosphorylation of glutamine by glutamine synthetase.
D) all of the above.
E) None of the answers is correct.

F) B) and C)
G) A) and B)

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Which of the following is a vasodilator that is derived from histidine?


A) epinephrine
B) norepinephrine
C) histamine
D) adenosine
E) prostacyclin

F) D) and E)
G) A) and E)

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What is catalytic substrate channeling?

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Channeling increases the catalytic rate,...

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Amino acid synthesis is primarily regulated by


A) turnover.
B) diet.
C) urea excretion.
D) allosteric enzyme regulation.
E) All the answers are correct.

F) B) and D)
G) All of the above

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