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DNA polymerase III ______.


A) is needed for adding nucleotides during mRNA synthesis
B) synthesizes new DNA only in the 5' to 3' direction
C) cannot add nucleotides to the lagging strand
D) synthesizes an RNA primer

E) B) and D)
F) A) and B)

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If the wild type DNA sequence reads THE CAT ATE THE BIG RAT, what type of mutation would change the sequence to THE CAT ATE THE BAG RAT?


A) Point
B) Nonsense
C) Insertion
D) Deletion
E) Silent

F) A) and C)
G) B) and D)

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Eukaryotic chromosomes differ from bacterial chromosomes because only eukaryotes have _______.


A) histone proteins
B) chromosomes in a nucleus
C) several to many chromosomes
D) elongated, not circular, chromosomes
E) All of the choices are correct.

F) None of the above
G) A) and C)

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The _____ is all of the genetic material of a cell.


A) proteome
B) plasmid
C) genome
D) chromosome
E) prophage

F) A) and C)
G) A) and B)

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Which of the following is not true of an organism's genotype?


A) It is inherited.
B) It contains structural genes that code for proteins.
C) It has expressed traits governed by the genes.
D) It has regulatory genes that control gene expression.
E) It contains genes that code for RNA.

F) C) and D)
G) All of the above

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A nucleosome is a linear chromosome wound around the _______.


A) nuclear membrane
B) rRNA
C) mRNA
D) histone
E) nucleolus

F) B) and D)
G) A) and D)

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The operon segment composed of the gene that codes for a protein repressor is called the ________.


A) operator
B) structural locus
C) regulator
D) promoter

E) None of the above
F) A) and B)

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DNA polymerase can catalyze a dehydration synthesis reaction only at the 3' carbon of the daughter strand of DNA. This means that _______.


A) the antiparallel nature of the parent molecules determine that the leading strand must be grown in fragments away from the fork and the lagging strand is synthesized continuously
Toward the fork
B) Okazaki fragments extend toward the replication fork as the parent strands are unzipped by helicase
C) since the strands are antiparallel, one strand will grow toward the fork as it opens, and the other strand will grow in fragments away from the fork
D) the leading and lagging strands extend in the 3' - 5' direction toward the replication fork as the nucleotide bases are exposed

E) All of the above
F) B) and C)

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The process in which mutations are removed and the correct bases added is called ________.


A) transduction
B) excision repair
C) frameshift
D) back-mutation
E) transformation

F) A) and E)
G) B) and D)

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If a codon for alanine is GCA, then the anticodon is ______.


A) GCA
B) CGT
C) ACG
D) CGU
E) UGC

F) B) and C)
G) B) and E)

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The fields of genomics and proteomics differ in that _______.


A) the field of genomics involves the study of DNA replication and the field of proteomics refers to the study of transcription and translation
B) genomics is the study of an organism's chromosomes and proteomics is the study of transcription and translation of proteins
C) genomics refers to the study of an organism's entire genome, whereas proteomics is the study of expressed proteins
D) genomics is the study of an organism's chromosomes and the resulting proteins are studied in the field of proteomics

E) A) and C)
F) C) and D)

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Which of the following is incorrect about transfer RNA?


A) It has a bottom hairpin loop with an anticodon.
B) It has an anticodon that is complementary to a codon.
C) It contains a binding site for an amino acid.
D) The initiator tRNA that binds to the P site has the anticodon UAC.
E) The initiator tRNA in bacteria carries tryptophan.

F) D) and E)
G) A) and B)

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Each nucleotide is composed of _______.


A) one phosphate, one nitrogenous base, and one sugar
B) one phosphate, one nitrogenous base, and two sugars
C) two phosphates, one nitrogenous base, and one sugar
D) two phosphates, one nitrogenous base, and two sugars
E) one phosphate, two nitrogenous bases, and one sugar

F) A) and C)
G) B) and D)

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In order for protein synthesis to begin, which of the following statements reflects the correct sequence of events?


A) The 3' end of the mRNA binds to the small ribosomal subunit and the AUG anticodon on the tRNA base pairs with the UAC codon on the mRNA, allowing the large ribosomal
Subunit to attach.
B) The AUG codon on mRNA base pairs with the UAC anticodon on tRNA allowing the small and large ribosomal subunits to join the complex.
C) Translation begins when the ribosome translocates from the A site to the P site on the mRNA
D) The 5' end of the mRNA binds to the small ribosomal subunit, and the large subunit joins, creating the P and A sites where reactions between codons on the mRNA and anticodons

E) C) and D)
F) All of the above

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A bacterial cell has replicated its plasmid, and when this cell divides into 2 daughter cells, each cell receives one copy of the plasmid. This is an example of horizontal gene transfer.

A) True
B) False

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Which of the following additions have been made to principles of the central dogma of biology?


A) DNA information cannot be converted into RNA information.
B) Protein information can be converted into DNA information.
C) RNA can be used to regulate gene function.
D) DNA codes for proteins.

E) A) and D)
F) A) and C)

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The transfer of DNA fragments from a dead cell to a live, competent recipient cell that results in a changed recipient cell is termed ________.


A) transduction
B) conjugation
C) transformation
D) transmission
E) mitosis

F) A) and C)
G) A) and E)

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Recombinant organisms are those that have received new DNA in the form of a conjugated plasmid; genetically engineered cells are not considered recombinant.

A) True
B) False

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Introns have no detectable functions.

A) True
B) False

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The site where the old DNA strands separate and new DNA strands will be synthesized is called the ________.


A) primer
B) Okazaki fragment
C) template
D) rolling circle
E) replication fork

F) A) and B)
G) None of the above

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