Question 1

A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

Accepted Answer

A) True 
 B)False

Question 2

The most common immunoglobulin deﬁciency is an IgG deﬁciency.

Accepted Answer

A) True 
 B)False  True

Question 3

Atopy and anaphylaxis are hypersensitivities in the category(ies)  _______.

Accepted Answer

A)   type I only
B)   type I and type IV
C)   type IV only
D)   type I, type II, and type III
E)   type I, type II, type III, and type IVF) D) and E)
G) C) and D)

Question 4

Immunopathology is de?ned as _______.

Accepted Answer

A)   the study of AIDS
B)   the study of immunode?ciencies
C)   the study of autoimmune diseases
D)   the study of immune imbalance, whether hyper- or hypoactivityE) A) and B)
F) A) and C)

Question 5

Which of the following is not true of type III hypersensitivity?

Accepted Answer

A)   It involves an immune complex reaction.
B)   It involves production of IgE antibodies.
C)   The Arthus reaction is a local response.
D)   Antigen-antibody complexes are deposited in the basement membrane of epithelial tissues.
E)   Serum sickness is a systemic response.F) All of the above
G) C) and D) B

Question 6

Allergic reactions to penicillins are considered a/an _______ hypersensitivity.

Accepted Answer

A)   T-cell-mediated
B)   antibody-mediated
C)   immune complex-mediated
D)   immediate
E)   Both T-cell-mediated and antibody-mediated are correct.F) A) and B)
G) C) and D)

Question 7

The potential for hemolytic disease of the newborn occurs when _______.

Accepted Answer

A)   fetal Rh- cells enter an Rh+ mother
B)   fetal Rh+ cells enter an Rh+ mother
C)   maternal Rh- cells enter an Rh+ fetus
D)   fetal Rh+ cells enter an Rh- mother
E)   maternal Rh+ cells enter an Rh- fetusF) A) and C)
G) C) and E)

Question 8

All of the following are involved in type II hypersensitivity except ______.

Accepted Answer

A)   IgE
B)   IgM
C)   complement
D)   foreign cells
E)   IgGF) A) and E)
G) A) and C)

Question 9

A chronic, local allergy such as hay fever is considered ______.

Accepted Answer

A)   systemic anaphylactic
B)   antibody-mediated
C)   atopic
D)   T-cell-mediated
E)   delayedF) D) and E)
G) A) and D)

Question 10

Food allergies include gastrointestinal symptoms and often hives.

Accepted Answer

A) True 
 B)False

Question 11

Autoimmune diseases and immunodeﬁciencies are studied and treated by immunopathologists.

Accepted Answer

A) True 
 B)False

Question 12

High levels of tryptase in the blood is indicative of _______.

Accepted Answer

A)   a viral and/or fungal infection
B)   high levels of degranulating mast cells suggesting an allergic reaction
C)   overuse of dietary supplements
D)   a bacterial infectionE) All of the above
F) None of the above

Question 13

What may result when grafted tissue such as bone marrow contains passenger lymphocytes?

Accepted Answer

A)   Host rejection of graft
B)   Hypogammaglobulinemia
C)   Graft versus host disease
D)   Formation of autoantibodiesE) A) and D)
F) C) and D)

Question 14

Predict why insect stings and medication injections more often provoke anaphylactic shock, as compared to other allergens found in food or in air.

Accepted Answer

A)   Chemicals from insects cause a combination of antibody types to be produced, resulting in much larger amounts of total antibody.
B)   The allergens go directly into the blood in large amounts, compared to allergens entering the digestive tract or respiratory tract.
C)   Histamine is overproduced as a result of injected chemicals.
D)   Chemicals injected as medications cause problems in immune response, resulting in a reduced immune coverage.E) B) and D)
F) B) and C)

Question 15

Eczema is an autoimmune disorder.

Accepted Answer

A) True 
 B)False

Question 16

Autoantibodies cause tissue injury in all of the following diseases except _______.

Accepted Answer

A)   tuberculin reaction
B)   myasthenia gravis
C)   rheumatoid arthritis
D)   Graves' disease
E)   multiple sclerosisF) A) and C)
G) B) and E)

Question 17

A second encounter with an allergen that causes a response is called the ______ dose.

Accepted Answer

A)   sensitizing
B)   provocative
C)   allergic
D)   hypersensitivity
E)   desensitizingF) A) and B)
G) A) and C) B

Question 18

The study of diseases associated with excesses and deﬁciencies of the immune system is _______.

Accepted Answer

A)   epidemiology
B)   histopathology
C)   hemopathology
D)   humoralpathology
E)   immunopathologyF) A) and B)
G) C) and D)

Question 19

Human blood types involve all of the following except _______.

Accepted Answer

A)   MHC genes
B)   genetically determined glycoprotein markers
C)   genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors
D)   ABO antigen markers
E)   inheritance of two of three possible allelesF) All of the above
G) B) and C)

Question 20

Infection with enteroviruses, such as rotavirus and cytomegalovirus, has been implicated in the onset of type I diabetes. This area of research involves the study of ______.

Accepted Answer

A)   forbidden clones
B)   the gut microbiome
C)   sequestered antigens
D)   molecular mimicryE) C) and D)
F) None of the above

Exam 16: Disorders in Immunity

A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

Correct AnswerverifiedShow Answer

The most common immunoglobulin deﬁciency is an IgG deﬁciency.

Correct AnswerverifiedTrue

Atopy and anaphylaxis are hypersensitivities in the category(ies) _______.

Correct AnswerverifiedShow Answer

Immunopathology is de?ned as _______.

Correct AnswerverifiedShow Answer

Which of the following is not true of type III hypersensitivity?

Correct AnswerverifiedB

Allergic reactions to penicillins are considered a/an _______ hypersensitivity.

Correct AnswerverifiedShow Answer

The potential for hemolytic disease of the newborn occurs when _______.

Correct AnswerverifiedShow Answer

All of the following are involved in type II hypersensitivity except ______.

Correct AnswerverifiedShow Answer

A chronic, local allergy such as hay fever is considered ______.

Correct AnswerverifiedShow Answer

Food allergies include gastrointestinal symptoms and often hives.

Correct AnswerverifiedShow Answer

Autoimmune diseases and immunodeﬁciencies are studied and treated by immunopathologists.

Correct AnswerverifiedShow Answer

High levels of tryptase in the blood is indicative of _______.

Correct AnswerverifiedShow Answer

What may result when grafted tissue such as bone marrow contains passenger lymphocytes?

Correct AnswerverifiedShow Answer

Predict why insect stings and medication injections more often provoke anaphylactic shock, as compared to other allergens found in food or in air.

Correct AnswerverifiedShow Answer

Eczema is an autoimmune disorder.

Correct AnswerverifiedShow Answer

Autoantibodies cause tissue injury in all of the following diseases except _______.

Correct AnswerverifiedShow Answer

A second encounter with an allergen that causes a response is called the ______ dose.

Correct AnswerverifiedB

The study of diseases associated with excesses and deﬁciencies of the immune system is _______.

Correct AnswerverifiedShow Answer

Human blood types involve all of the following except _______.

Correct AnswerverifiedShow Answer

Infection with enteroviruses, such as rotavirus and cytomegalovirus, has been implicated in the onset of type I diabetes. This area of research involves the study of ______.

Correct AnswerverifiedShow Answer

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