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The junction of a neuron with another cell is a/an ________.


A) synapse
B) ganglion
C) receptor
D) effector

E) C) and D)
F) A) and C)

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Which of the following descriptions of glial cells is mismatched?


A) Microglia - provide support for the neuron cell body
B) Astrocytes - blood-brain barrier
C) Oligodendrocytes - form myelin sheaths
D) Ependymal cells - produce cerebrospinal fluid
E) Ependymal cells - choroid plexus

F) A) and C)
G) A) and B)

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Match the term with the correct definition. -Resting membrane potential


A) Small change in the resting membrane potential confined to a small area
B) Charge difference across the plasma membrane when the cell is in an unstimulated state
C) Larger change in resting membrane potential that spreads over entire surface of a cell
D) Membrane becomes more positive when Na+ diffuse into cell
E) Return to the resting membrane potential

F) All of the above
G) A) and B)

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The function of acetylcholinesterase is to


A) open voltage-gated Na+ channels.
B) break down acetylcholine in the synapse.
C) produce an IPSP on the postsynaptic membrane.
D) metabolize norepinephrine.

E) A) and B)
F) All of the above

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Match the term with the correct definition. -Action potential


A) Small change in the resting membrane potential confined to a small area
B) Charge difference across the plasma membrane when the cell is in an unstimulated state
C) Larger change in resting membrane potential that spreads over entire surface of a cell
D) Membrane becomes more positive when Na+ diffuse into cell
E) Return to the resting membrane potential

F) B) and D)
G) C) and D)

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Which inhibitory neurotransmitter is blocked in strychnine poisoning?


A) Glycine
B) Acetylcholine
C) Glutamate
D) Adenosine

E) A) and C)
F) A) and B)

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Which of the following is NOT true of reactive astrocytosis?


A) Injury site is blocked off
B) Scars limit regeneration
C) Causes the spread of inflammation
D) Reduces injury to surrounding tissue

E) A) and B)
F) None of the above

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An action potential


A) occurs when the local potential reaches threshold level.
B) propagates across the plasma membrane in a decremental fashion.
C) has no repolarization phase.
D) is an example of negative feedback.
E) cannot transmit information.

F) None of the above
G) A) and B)

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Match the following concerning concentration differences across the plasma membrane. -Requires ATP


A) Concentration of K+
B) Concentration of Na+ and Cl−
C) Negatively charged proteins
D) Sodium-potassium pump
E) Plasma membrane is more permeable to this ion because of leak ion channels

F) All of the above
G) A) and E)

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A decrease in the number of voltage-gated Ca2+ ion channels in the presynaptic terminal would


A) enhance transmission across the synapse.
B) reduce or inhibit transmission across the synapse.
C) have no effect on transmission across the synapse.
D) alter receptors on the postsynaptic membrane.
E) increase exocytosis.

F) None of the above
G) A) and B)

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Nerve fibers are also called ________.

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Sensory neurons carrying action potentials from pain receptors synapse within the spinal cord with interneurons. These interneurons synapse with motor neurons leading back to an effector and ascending neurons that carry action potentials toward the brain. This is an example of a/an ________ pathway.


A) convergent
B) divergent
C) reverberating
D) sensory
E) bifurcated

F) C) and D)
G) B) and E)

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Which of these happens first in a cholinergic synaptic transmission?


A) Acetylcholine diffuses across the synaptic cleft.
B) A postsynaptic potential is produced.
C) Sodium ions enter the postsynaptic cell.
D) The synaptic vesicles release acetylcholine.
E) Acetylcholine binds to ligand-gated ion channels.

F) A) and E)
G) A) and D)

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Chemical synapses are characterized by


A) the release of neurotransmitter by the presynaptic terminal.
B) connexons that connect the pre- and postsynaptic cells.
C) the presence of receptors for neurotransmitters on the presynaptic terminal.
D) the absence of gap junctions.
E) receptors located only on the presynaptic terminal.

F) A) and E)
G) A) and D)

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Compounds classified as ________ alter synaptic transmission by changing neurotransmitter receptor numbers or affecting the breakdown and/or removal of neurotransmitter.


A) neuromodulators
B) inhibitory neurotransmitters
C) excitatory neurotransmitters
D) neurohormones

E) C) and D)
F) B) and D)

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Which of the following situations occurs in electrically excitable cells?


A) When Na+ channels open, K+ channels close.
B) The sodium-potassium pump moves Na+ into the cell.
C) Depolarization causes voltage-gated Na+ channels to open.
D) Ligand-gated Na+ channels are opened by high extracellular Ca2+ levels.
E) Proteins tend to diffuse out of the cell.

F) A) and B)
G) A) and C)

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Synaptic vesicles contain neurotransmitters and are present in the ________.


A) dendrites
B) cell body
C) axolemma
D) presynaptic terminals
E) trigger zone

F) B) and E)
G) A) and D)

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A stimulus either causes an action potential or it doesn't. This is called ________.


A) an all-or-none response
B) a graded response
C) a latent period response
D) a relative refractory response
E) a local response

F) None of the above
G) C) and D)

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In an EPSP (excitatory postsynaptic potential) , there is a


A) net movement of Na+ out of the cells.
B) net movement of Cl− into the cells.
C) decrease in action potential amplitude.
D) local hyperpolarization.
E) local depolarization.

F) B) and E)
G) B) and D)

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If the extracellular fluid around a neuron is replaced with an isotonic saline solution that contains K+ and other solutes at concentrations very close to the extracellular fluid concentrations of a normal cell, the result is


A) no resting membrane potential.
B) hyperpolarized membrane.
C) depolarized membrane.
D) a resting membrane potential close to its normal value.
E) None of the choices are correct.

F) C) and D)
G) B) and E)

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