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Which of the following layers of the filtration membrane is closest to the plasma?


A) Podocytes
B) Macula densa
C) Glomerular endothelium
D) The basement membrane
E) Parietal layer of Bowman capsule

F) All of the above
G) A) and D)

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Autoregulation in the kidney involves changes in the degree of ________.


A) constriction of afferent arterioles
B) sympathetic stimulation
C) aldosterone secretion
D) ADH secretion
E) None of the choices are correct

F) C) and E)
G) None of the above

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Decreased ADH levels results in a urine high in ________.


A) K+
B) water content
C) glucose content
D) bicarbonate content
E) H+

F) A) and D)
G) C) and D)

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In glomerulonephritis, proteins, and white blood cells enter the filtrate resulting in


A) increased reabsorption of water.
B) increased reabsorption of Na+.
C) increased secretion of Na+.
D) increased urine output.
E) decreased urine output.

F) A) and E)
G) C) and D)

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Urine flows through the ureters to the bladder as the result of ________.


A) gravity
B) a pressure gradient
C) a concentration gradient
D) peristaltic contractions
E) osmotic gradient

F) None of the above
G) C) and E)

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Hydrogen ions are secreted into the filtrate by


A) both the proximal and distal convoluted tubules.
B) both the collecting duct and Bowman capsule.
C) both the loop of Henle and the distal convoluted tubule.
D) both the proximal convoluted tubule and the loop of Henle.
E) loop of Henle only.

F) A) and B)
G) B) and D)

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The kidney dialysis machine is an example of a mechanical ________ system.


A) active transport
B) countercurrent
C) cotransport
D) sorting

E) A) and C)
F) All of the above

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Which of the following would reduce the glomerular filtration rate?


A) Vasoconstriction of the efferent arteriole
B) A drop in colloid osmotic pressure
C) Vasodilation of the afferent arteriole
D) Vasoconstriction of the afferent arteriole
E) An increase in osmotic pressure in the Bowman capsule

F) B) and C)
G) C) and D)

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Arrange the following in correct order. (1) Cotransport molecule binds to Na+ and glucose (2) Establish Na+ concentration gradient between tubular cells and tubular lumen (3) Sodium and glucose moved into tubular cell (4) Active transport of Na+ from tubular cells to interstitial area


A) 2, 1, 3, 4
B) 4, 2, 1, 3
C) 1, 3, 4, 2
D) 2, 4, 1, 3
E) 1, 2, 3, 4

F) B) and E)
G) A) and C)

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The network of capillaries that is located in Bowman capsule is called the ________.


A) vasa recta
B) glomerulus
C) peritubular capillary
D) proximal convoluted capillary
E) efferent arteriole

F) C) and D)
G) A) and D)

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Urine is carried from the kidneys to the urinary bladder by the ________.


A) urethra
B) ureter
C) calyces
D) renal columns
E) renal tubules

F) A) and E)
G) A) and C)

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Glucose and amino acids are reabsorbed from the glomerular filtrate by the ________.


A) renal corpuscle
B) proximal convoluted tubule
C) distal convoluted tubule
D) glomerular capillaries
E) collecting duct

F) All of the above
G) None of the above

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Total saturation of protein transporters for a given solute in the renal tubules would result in ________.


A) reabsorption of all the solute
B) a renal clearance of zero
C) a net filtration pressure of 1.0
D) appearance of that solute in the urine
E) absence of that solute from the urine

F) A) and B)
G) D) and E)

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Which of the following is NOT an action of angiotensin II?


A) Vasoconstriction of arterioles
B) Increases thirst
C) Increases ADH secretion
D) Decreases peripheral resistance
E) Increases aldosterone secretion

F) C) and D)
G) B) and C)

Correct Answer

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The collecting ducts and distal convoluted tubules


A) reabsorb glucose.
B) collect filtrate from Bowman capsule.
C) actively transport Na+ but not Cl−.
D) vary in their permeability to water relative to the amounts of ADH present.
E) do not alter their permeability to water.

F) A) and E)
G) A) and D)

Correct Answer

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Which of the following structures is a capillary?


A) Glomerulus
B) Loop of Henle
C) Collecting duct
D) Bowman capsule
E) Proximal convoluted tubule

F) C) and D)
G) C) and E)

Correct Answer

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In the sodium-hydrogen antiport system,


A) both Na+ and H+ are transported into the tubular lumen.
B) both Na+ and H+ are transported into the tubular cell.
C) Na+ are transported into the cell; H+ are transported out of the cell.
D) Na+ are transported into the tubular lumen; H+ are transported into the cell.
E) Na+ are transported out of the cell; H+ are transported into the cell.

F) A) and B)
G) None of the above

Correct Answer

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A hospital patient produces 4 mL/min of urine with a urea concentration of 8 mg/mL. Venous blood draw reveals urea concentration of 0.4 mg/mL. What is the percentage of cleared urea from glomerular filtrate?


A) 40%
B) 56%
C) 64%
D) 72%
E) 80%

F) A) and B)
G) All of the above

Correct Answer

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Diuretics that inhibit Na+ reabsorption are called ________.


A) xanthines
B) osmotic diuretics
C) thiazide diuretics
D) carbonic anhydrase inhibitors
E) ADH inhibitors

F) B) and C)
G) B) and E)

Correct Answer

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The active transport of substances into the filtrate is called tubular ________.


A) filtration
B) reabsorption
C) secretion
D) elimination
E) excretion

F) A) and D)
G) A) and E)

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