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HIV infects cells by recognizing the cell-surface markers with its own


A) DNA.
B) glycoproteins.
C) reverse transcriptase.
D) capsid protein.
E) enzymes.

F) C) and D)
G) B) and E)

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Gardasil is marketed as a cervical cancer vaccine,but it is actually a human papilloma virus (HPV) vaccine.Why is this done?


A) The virus multiplies more rapidly in cancerous cells.
B) Cancer cells are particularly susceptible to viral infection.
C) Genital warts is a sign of cancer.
D) HPV in the cervical epithelial cells may cause the cells to become cancerous.

E) A) and C)
F) A) and D)

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Each HIV particle possesses a ________ on its surface,called gp120,that precisely binds to a protein,called CD4,that is found on the surfaces of the immune system cells called macrophages and T cells.


A) nucleic acid
B) phospholipid
C) polysaccharide
D) glycolipid
E) glycoprotein

F) A) and B)
G) None of the above

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The direction of genetic information transfer in a retrovirus (such as HIV) is


A) DNA to mRNA to protein.
B) RNA to DNA to mRNA to protein.
C) DNA to protein.
D) RNA to mRNA to protein.
E) RNA to protein.

F) B) and E)
G) A) and B)

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The SARS virus is a member of the family of viruses called ________.

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Viruses can ________ only after they have entered a host cell,and only by using the host's cellular machinery.

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Recently a class of infectious proteins with no associated nucleic acid have been identified.They are referred to as


A) bacteriophages.
B) latent viruses.
C) viroids.
D) prions.
E) virions.

F) B) and E)
G) A) and D)

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Benign Vibrio cholerae becomes pathogenic by all of the following steps except


A) a bacteriophage introduces a gene coding for the cholera toxin.
B) the cholera toxin gene is incorporated into the benign Vibrio cholerae chromosome.
C) the benign host is transformed into a disease-causing agent by the toxin.
D) the cholera toxin gene is translated.
E) a bacteriophage binds only to benign Vibrio cholerae without pili.

F) A) and D)
G) A) and B)

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The HIV virus is considered a(n) ________ virus,because after getting integrated into the host cell chromosomes,it does not begin replicating immediately.


A) phage
B) latent
C) transforming
D) benign
E) inducible

F) D) and E)
G) None of the above

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Tetracycline is effective against viruses because it disrupts the action of the viral ribosomes.

A) True
B) False

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Which of the following is a unique feature of viruses that separates them from bacteria?


A) They are generally smaller.
B) They are often highly toxic.
C) They lack proteins.
D) They have different nucleotides in their hereditary material.
E) They cannot exist outside of a host cell.

F) B) and C)
G) None of the above

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While they are simple relative to cells,viruses often have a very diverse collection of components.Which one of the following choices is LEAST likely to be found as part of a virus?


A) proteins with functional binding sites
B) membrane components
C) single-stranded DNA
D) ribosomes
E) glycoproteins

F) B) and C)
G) A) and E)

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Outside the protein sheath,many viruses have a(n)________ made of protein,lipid,and carbohydrate.

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A scientist is studying the lysogenic cycle of the lambda 1 phage of Escherichia coli.This means that she is investigating


A) the integration and stabilizing of the lambda 1 phase into a host cell's genome.
B) the integration of the bacteria's genome with the viral genome outside of the bacteria's cell wall.
C) the integration of the viral genome into the ribosomes present in the bacteria to direct protein synthesis for the capsid formation.
D) the integration and stabilizing of a virus into its capsid,which provides protection until conditions are better for reproduction.

E) A) and C)
F) B) and D)

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Viruses infect every organism that has been investigated for their presence.However,viruses can only replicate in


A) very limited conditions,depending on their capsid type.
B) a very limited manner if they are a retrovirus.
C) a very limited manner depending on their envelope capability with the host's cell membrane or cell wall.
D) their lytic stage outside the host cell membrane.
E) a very limited number of the host's cells.

F) A) and E)
G) C) and D)

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The onset of AIDS is often accompanied by


A) a steep drop in T cell numbers.
B) macrophage infection.
C) a positive HIV test.
D) lung infections and other opportunistic infections.
E) Kaposi's sarcoma.

F) B) and E)
G) A) and E)

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Which of the following statements about TSEs (transmissible spongiform encephalopathies) is false?


A) TSEs include scrapie in sheep,mad cow disease,chronic wasting disease in deer and elk,and kuru and variant Creutzfeldt-Jakob disease in humans.
B) The incidence of Creutzfeldt-Jakob disease in humans increased after an outbreak of mad cow disease in England,suggesting that mad cow disease may be transmitted to humans.
C) Viroids are the likely cause of TSEs.
D) TSEs do not seem to be affected by treatments that would eliminate nucleic acid-based diseases.
E) Infectious TSE preparations do not seem to contain DNA or RNA.

F) A) and E)
G) All of the above

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If a virus enters the lytic phase in a host's cell,it will cause the host cell to


A) reject the virus.
B) shrink because of the loss of cytoplasm that has been used in the synthesis of viral DNA.
C) lyse due to the action of enzymes.
D) replicate itself at a higher than normal frequency.
E) initiate an attack on the virus.

F) A) and B)
G) A) and C)

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Viruses that become established as stable parts of the host cell genome are called


A) lethal.
B) potent.
C) temperate.
D) virulent.

E) A) and B)
F) B) and C)

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Which of the following statements about emerging viruses is false?


A) Emerging viruses are able to "jump" from one species to another.
B) Hantavirus,which causes a hemorrhagic-type fever,originates in deer mice.
C) Ebola is an emerging virus of unknown origins that can have a mortality rate in excess of 50%.
D) The emerging virus SARS is a coronavirus.
E) The stable genome of the SARS virus makes it an unlikely candidate for vaccine development.

F) B) and C)
G) A) and E)

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