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Apoptosis refers to cell death and


A) is always biologically detrimental to an organism.
B) can be programmed and is essential to normal development.
C) is the accumulation of genetic errors.
D) is a failure in the translation or transcription mechanism.
E) is any failure of the genetic machinery to work correctly.

F) B) and C)
G) A) and E)

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What part of a tRNA molecule will base pair with the codon of a mRNA molecule?


A) DNA sequence
B) anticodon
C) amino acid binding site
D) amino acid
E) promoter site

F) B) and D)
G) A) and E)

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In eukaryotes, control of gene expression is accomplished by


A) translational control in cytoplasm after mRNA leaves the nucleus and before protein is produced.
B) transcriptional control in the nucleus based on which genes are transcribed and how fast they are transcribed.
C) posttranscriptional control in the nucleus after DNA is transcribed, including the speed with which mRNA leaves the nucleus.
D) posttranslational control in the cytoplasm that occurs after protein synthesis.
E) All of the answer choices are correct.

F) B) and C)
G) A) and D)

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Identify the amino acids that would be assembled based upon the following codons: CGG AUA GAC GUA.

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CGG would code for arginine.
A...

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Initiation, elongation, and termination are three stages in


A) DNA replication.
B) error correction by proofreading enzymes.
C) mRNA processing.
D) translation.
E) intron removal.

F) C) and D)
G) A) and D)

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The site of translation is the


A) nucleus.
B) nucleolus.
C) ribosome.
D) ribozyme.
E) mitochondria.

F) B) and C)
G) C) and E)

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Which of the following is a frameshift mutation of the nucleotide sequence CATUAUCCC?


A) CATTUAUCCC
B) ATUAUCCC
C) CTUAUCCC
D) CATUAUCGC
E) All of the answer choices are frameshift mutations.

F) B) and D)
G) A) and D)

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When the sheep Dolly was successfully cloned, it was produced by growing an in vitro fertilized egg where the normal egg nucleus had been removed and replaced by a nucleus from an adult. Since this nucleus was from an older mature animal, which of the following would be a reasonable expectation?


A) The nucleus from the older mature animal would have additional Barr bodies.
B) The nucleus from the older mature animal would contain DNA with many mutations.
C) The nucleus from the older mature animal would contain chromosomes with shorter telomeres.
D) The nucleus from the older mature animal would have chromosomes with longer telomeres.
E) The nucleus from the older mature animal would have a higher concentration of mRNA.

F) A) and D)
G) B) and D)

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Messenger RNA is produced in the


A) cytoplasm.
B) ribosomes.
C) nucleus.
D) endoplasmic reticulum.
E) lysosome.

F) B) and C)
G) A) and E)

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Transcription of part of a DNA molecule with a nucleotide sequence of AAACAACTT results in a mRNA molecule with the complementary sequence of


A) GGGAGAACC.
B) UUUGUUGAA.
C) TTTGAAGCC.
D) CCCACCTCC.
E) AAACAACTT.

F) B) and C)
G) B) and D)

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Which of the classes of RNA molecules is produced in the nucleolus?


A) ribosomal RNA
B) transfer RNA
C) messenger RNA
D) primary mRNA transcript
E) ribozymes

F) B) and E)
G) All of the above

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An oncogene is


A) a viral gene with no relation to the host cell's genes.
B) a mutated form of a proto-oncogene.
C) a bacterial gene that causes cancer in the host.
D) always seen in human cancer cells.
E) a gene that turns off cellular reproduction.

F) C) and D)
G) B) and D)

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Which of the following is true about oncogenes?


A) Oncogenes are normal genes that have undergone a mutation.
B) Oncogenes cause cell division to slow down.
C) When mutated, oncogenes turn into proto-oncogenes.
D) Oncogenes increase apoptosis in surrounding cells.
E) All of the answer choices are true statements about oncogenes.

F) C) and D)
G) All of the above

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Which of the following processes takes place during transcription?


A) attachment of a ribosome to mRNA
B) growth of a polypeptide chain
C) binding of two tRNA molecules/ribosome
D) liberation of polypeptide from ribosome
E) production of mRNA

F) B) and E)
G) None of the above

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The function of the regulator gene is to


A) code for enzymes in a metabolic pathway.
B) serve as an on/off switch for transcription.
C) code for a repressor molecule that can bind to the operator.
D) bind to the RNA polymerase molecule.
E) bind to the promoter.

F) A) and B)
G) D) and E)

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During translation, which of the following is involved in translation?


A) mRNA
B) tRNA
C) rRNA
D) ribosome
E) All of the answer choices are involved in translation.

F) C) and D)
G) C) and E)

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Which of the following occurs when lactose is present in the environment of E. coli?


A) The lac repressor binds to the promoter.
B) RNA polymerase binds to the operator.
C) No genes are transcribed.
D) RNA polymerase binds to the promotor.
E) Lactose binds to the promotor.

F) D) and E)
G) All of the above

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What are transcription factors?


A) Transcription factors are proteins that help the repressor bind to the operator.
B) Transcription factors are proteins that help RNA polymerase bind to the promoter.
C) Transcription factors are proteins that help DNA polymerase bind to the promoter.
D) Transcription factors are proteins that help helicases bind to the operator.
E) Transcription factors are proteins that help the operator bind to the repressor.

F) A) and D)
G) A) and B)

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If the protein coat of a virus that infects a bacterium is labeled with radioactive sulfur while the DNA of the virus is labeled with radioactive phosphorus, over time


A) both the sulfur and the phosphorus will be found within the bacterium.
B) only the sulfur will be found inside the bacterium.
C) only the phosphorus will be found inside the bacterium.
D) both the sulfur and the phosphorus will be found outside the bacterium.
E) the radioactivity of the sulfur and phosphorus will decay very quickly and not be detectable.

F) A) and E)
G) A) and C)

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Which of the following is true about RNA?


A) The structure is a double helix.
B) The bases are held together by hydrogen bonds.
C) The bases are complementary to each other.
D) It contains deoxyribose sugar.
E) It is composed of the nucleotides adenine, guanine, cytosine, and uracil.

F) A) and D)
G) C) and D)

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